Mass Industry Contraction: Major pharmaceutical companies including Merck (6,000 layoffs), Moderna, Bristol Myers Squibb, and Novartis have implemented widespread workforce reductions in 2025, totaling thousands of job cuts as the industry faces declining revenues and patent expirations.
Historic Trust Collapse: Public confidence in pharmaceutical companies has plummeted to record lows, with only 20% of Americans expressing positive views of the industry, while 59% believe business leaders deliberately mislead the public on health issues.
Regulatory and Legal Pressures: The Trump administration has launched aggressive enforcement against pharmaceutical advertising, while lawsuits over products like Tylenol threaten billions in liability, culminating in major stock declines and investor uncertainty.
Grassroots MAHA Movement: The "Make America Healthy Again" movement has gained significant political influence, successfully pushing policy changes that challenge pharmaceutical dominance and promote health sovereignty, with global ripple effects across international markets.